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This website is intended to provide information about the ongoing PACIFICA clinical trial in myelofibrosis.

The PACIFICA clinical trial is a randomized, controlled phase 3 study of pacritinib versus Physician’s Choice1 in patients with primary myelofibrosis, post polycythemia vera myelofibrosis, or post essential thrombocythemia myelofibrosis with severe thrombocytopenia (platelet counts <50,000/μL).

1Physician's choice is limited to single drugs (as applicable per country) from the following list: corticosteroids, hydroxyurea, danazol, or low-dose ruxolitinib.